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High Total, Animal Protein Intake Ups Type 2 Diabetes Risk

Posted on Fri, May 09, 2014
High Total, Animal Protein Intake Ups Type 2 Diabetes Risk

Effect modified by sex and body mass index, with strongest association seen for obese women

MONDAY, April 21, 2014 (HealthDay News) -- High total and animal protein intake correlates with increased incidence of type 2 diabetes, according to a study published online April 10 in Diabetes Care.

Monique van Nielen, Ph.D., from Wageningen University in the Netherlands, and colleagues examined the long-term association between total, animal, and plant protein intake and the incidence of type 2 diabetes. Data were collected from 12,403 cases with incident type 2 diabetes from the European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study, and a stratified subcohort of 16,154 individuals from eight European countries. Participants were followed for an average of 12.0 years.

The researchers found that the incidence of type 2 diabetes was increased for those with high intake of total protein (per 10 g: hazard ratio [HR], 1.06: Ptrend < 0.001) and animal protein (per 10 g: HR, 1.05; Ptrend = 0.001), after adjustment for important diabetes risk factors and dietary factors. The effect was modified by sex (P < 0.001) and by body mass index (BMI) among women (P < 0.001). The correlations were stronger among women, especially obese women with a BMI >30 kg/m² (per 10 g animal protein: HR, 1.19) and were not significant for men. There was no correlation between plant protein intake with type 2 diabetes (per 10 g: HR, 1.04; Ptrend = 0.098).

"In view of the rapidly increasing prevalence of type 2 diabetes, limiting isoenergetic diets high in dietary proteins, particularly from animal sources, should be considered," the authors write.

Abstract
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