Smoking Has Negative Impact on Success of ACL Reconstruction

Posted on Mon, Jul 21, 2014
Smoking Has Negative Impact on Success of ACL Reconstruction

Negative effect on subjective and objective outcomes of anterior cruciate ligament reconstruction

THURSDAY, July 10, 2014 (HealthDay News) -- Cigarette smoking is associated with a negative impact on anterior cruciate ligament (ACL) reconstruction outcomes, according to a study published in the June 18 issue of The Journal of Bone & Joint Surgery.

Sung-Jae Kim, M.D., Ph.D., from the Yonsei University College of Medicine in South Korea, and colleagues conducted a retrospective review of 251 patients who underwent unilateral ACL reconstruction with use of bone-patellar tendon-bone autograft from January 2002 to August 2009. Preoperative values and 24-month postoperative findings were compared for nonsmokers, current smokers, and former smokers.

The researchers found that the three groups differed significantly in terms of postoperative mean side-to-side anterior knee translation (P = 0.003), mean Lysholm score (P < 0.001), and mean International Knee Documentation Committee (IKDC) subjective score (P < 0.001); there was no minimal clinically important difference seen in the difference in IKDC subjective score. Pack-years of exposure correlated with postoperative anterior translation (P = 0.015) and IKDC objective grade (odds ratio, 1.083; P = 0.002) in a dose-dependent manner. There was a significant difference for light, moderate, and heavy smokers in anterior translation (P = 0.038) and in the proportion of cases by IKDC objective grade (P = 0.013).

"Cigarette smoking appeared to have a negative effect on subjective and objective outcomes of ACL reconstruction, and heavy smokers showed greater knee instability," the authors write.

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